What We Know About the UPS Plane Crash in Louisville NYT | Top Stories By: Francesca Regalado and Michael Levenson 6 November 2025 at 05:16 At least 11 people died when a cargo plane crashed after takeoff in Louisville, Ky. The airport reopened Wednesday morning, but officials warned the death toll could rise. © Jon Cherry/Associated PressA plume of smoke rises from the site of a UPS cargo plane crash at Louisville Muhammad Ali International Airport on Tuesday.