On the face of it, watercolour painting should be the simplest of all the more popular painting media. The paper is both support and ground, the paint layer is thin, with a little binder of gum arabic and a diluent of plain water. Although some have tried using varnish and other protective layers, in the great majority of watercolour paintings, that’s all there is.

In practice, though, as anyone who has taken watercolour painting seriously knows, there’s a great deal more to it. Much of that is hard to see and can only be inferred from images of watercolour paintings.

Raphael’s The Miraculous Draft of Fishes (c 1515-16) is among the earliest large paintings made using opaque watercolour. Because of limitations in the manufacture of paper at the time, it was made on many sheets that have been mounted on canvas. At around 3 x 4 metres (10.5 x 13 feet), it’s huge by any standards, and even today would probably need to be painted on multiple sheets and mounted on added support.

Over three centuries later, the Pre-Raphaelite artist Marie Spartali Stillman painted her watercolours in layers, using a combination of transparent and opaque watercolour on paper that had been hot-pressed to give it a satin-smooth finish. When re-wetted with another layer of wet paint, watercolour usually becomes liquid again, resulting in the layers mixing. Great care and skill is required to apply wet watercolour on dry paint in the way that she did. Even then some paintings simply don’t work, the layers mix and that attempt has to be discarded. When successful, the end result can resemble layered oil paints, which don’t suffer the same problem when dry paint is overpainted.

The Childhood of Saint Cecily (1883) was one of the last paintings Stillman composed when she lived in Florence, as reflected in its idealised Tuscan background. As with so many paintings of saints, it departs from even the most inventive of hagiographies, here for the patron saint of music, Cecilia. The saint is shown playing a harp-like psaltery, while an angel adjusts the garland on her head. She has worked subtle patterns into the blue fabric on the arm of the angel, and in the side of the instrument. Flowers and hair have fine detail with sharp highlights, just as might be seen with oils.

Love’s Messenger (1885) is probably the finest of her single-figure paintings, and was her most successful ‘problem picture’. The woman stands by her embroidery at an outside window. On her right hand is a messenger dove/pigeon, to which a letter is attached. She clutches that letter to her breast with her left hand, implying that its contents relate to matters of the heart. The dove is being fed corn, which could either be its reward for having reached its destination (thus the woman is the recipient of the message), or preparation for its departure (she is the sender). Despite being exhibited at the Grosvenor Gallery in 1885, and elsewhere, this painting didn’t sell until after she had reworked the background in the 1890s, which must have been a feat in itself.

A detail view of Love’s Messenger shows how her watercolour technique results in a facture more closely resembling that of oils, although this painting is an extreme example with its use of tempera too. This was accomplished by using transparent watercolours more like oil glazes, and gouache (opaque watercolour) for details.

Her portrait of Beatrice (1896) refers to Dante’s Vita Nuova, through Dante Gabriel Rossetti’s popular translation into English. In this her first version, she shows Dante’s beloved Beatrice lost in contemplation while reading, an intimate insight set firmly in the Pre-Raphaelite mediaeval. This was exhibited at the New Gallery later that year.

This detail view of Beatrice provides more insight into her exacting technique.

Over the same period, other artists were developing techniques for use on cold-pressed paper with its coarser texture.

At a time when most watercolour painting was still disparagingly considered to be ‘drawing’ for routine topographic views, Alexander Cozens developed specialist techniques, such as keeping ‘reserved space’ to let his white paper ground show through, wet on wet as well as wet on dry application of paint, and scratching out. He also employed both transparent and opaque paints for different effects.

JMW Turner did a great deal to advance both technique and the critical reception of large watercolour works painted in the studio, although even today his oils are much better known, with a few exceptions such as his sublime paintings of the Rigi.

Towards the end of the nineteenth century, Winslow Homer earned his place as one of the greatest watercolour painters of America during a period spent in a fishing community in north-east England. The advanced techniques which he used are shown well in The Watcher, Tynemouth (1882), and include both transparent and opaque paints, rewetting and blotting to remove paint for highlights, scraping, application of wax to resist the adherence of paint, and the use of pure gum solution as a glaze. In this case, his paper is only lightly textured, though.

Perhaps the greatest exponent of these techniques was another American, John Singer Sargent.

Sargent’s most radical watercolours were painted when he stayed with various friends in the Bellevue Hotel, at the top of the Simplon Pass, in the summers before the First World War. While his family and friends whiled away their days in leisure, Sargent got them to pose for a unique series of informal portraits. They may have been reclining at leisure, but Sargent took those watercolours very seriously, and deployed an amazing array of techniques. Among the finest is his Simplon Pass: The Tease from the summer of 1911.

One of his most unusual techniques, used extensively here, is wax resist. Before applying paint, Sargent scribbled over areas intended to be vegetation, using a soft wax crayon, probably made from beeswax. On fairly rough paper, that wax is deposited unevenly, and when painted over using watercolour it shows the white paper through. This creates disruptive patterns of near-white in the midst of the greens, and a superb textural effect, as shown in this detail.

In complete contrast, Edward Robert Hughes’ Night with her Train of Stars of the following year has been painted in a controlled and meticulous manner, although it too uses advanced techniques, particularly in the sky and background. I suspect that some of the latter may have relied on the scattering of salt grains to impart its fine texture. In other passages he has allowed different colours to rewet and blur what would otherwise be sharp edges.

Of course, AI can now mimic these when provided with suitable original material to plagiarise. But there’s still nothing like an original painted by a master.

The Renaissance modernised the art of the late Middle Ages with realistic images that strived to resemble what we actually see, rather than presenting a world of stereotypes and symbols. This is best seen by comparing paintings of a common theme spanning the period, here those of the Madonna and Child.

Cimabué’s Maestà was painted in egg tempera for the main altar of the church of Santa Trinita in Florence, between 1280-90. Little attempt is made to distinguish surface textures, although some use is made of lightness and pattern in fabrics to depict their folds. Faces are uniform and devoid of expression or emotion, most turned in directions determined by its structured composition. There’s no sign of any landscape or other background, and no impression of reality.

While Ghirlandaio’s Madonna and Child from about 1470-75 was still painted in egg tempera, it’s much more realistic in its approach to the figures and the folds in fabrics. Modelling of the figures is still restrained, and there’s no natural background, but its intent is clearly to resemble a real mother and her infant.

Raphael’s Madonna della Sedia (Madonna of the Chair) from 1513-14 shows a thoroughly real and natural mother with two infants, every surface texture rendered as in life, with wisps of hair, differentiation between types of fabric, and convincing expressions and postures.

Many of the changes seen here in the Renaissance can be elaborated as follows:

• surface texture of skin, hair and fabrics;
• individual faces expressing emotions;
• telling stories using body language;
• individual natural posture;
• realistic landscape backgrounds;
• three-dimensional perspective projection with controlled vanishing points;
• varied composition;
• the air of reality;
• use of oil paints;
• increasing production of easel paintings;
• references to both secular and classical literature;
• introduction of new genres such as landscapes and secular paintings;
• direct patronage;
• independent and secular masters.

Technically the Renaissance provided the painter with all the tools for painting anything that might be seen in life. However, the great majority of paintings were commissioned for religious use, so depicted motifs drawn from the Bible and other Christian writing.

One of the early and most skilled practitioners of oil painting was the brilliant but short-lived Venetian master Giorgione, who has the added distinction of painting what was probably the first landscape painting of the southern Renaissance.

Giorgione’s revolutionary landscape The Tempest from just after 1500 remains enigmatic today, and may have religious references, but it marked the start of a new and wholly secular genre.

Late in the Italian Renaissance, emphasis shifted from its birthplace Florence to other centres such as Bologna and, most of all, Venice, where the effects of colour (Italian colore) came to dominate form and design (Italian disegno).

Jacopo Tintoretto’s Crucifixion from 1565 is over 5 metres (17 feet) high, and 12 metres (40 feet) across, larger than many frescoes of the Renaissance. He makes use of this space with a narrative technique based on the popular ‘multiplex’ form: its single image shows events at more than a single point in time, in an ingenious and modern manner.

Naturally, the painting centres on Christ crucified, but the two thieves executed beside him are not shown, as would be traditional, already hanging from their crosses. Instead, to the right of Christ, the ‘bad’ thief is still being attached to his cross, which rests on the ground. To the left of Christ, the ‘good’ thief is just being raised to the upright position.

Tintoretto’s Annunciation is thought to have been painted even later, in about 1582. Its composition is unusual by any contemporary standards, with natural rendering of brickwork, a wicker chair, and a splendidly realistic carpenter’s yard at the left. This is coupled with an aerial swarm of infants, at the head of which is the dove of the Holy Ghost in a small mandorla. Christ’s origins are here very real, tangible, and contemporary, in stark contrast to most traditional depictions of this scene.

If any single workshop brought the Renaissance to a close and moved on to what has become termed the Baroque it’s that of the Carraccis, initially in Bologna, then in Rome.

Annibale Carracci’s Latona and the Lycian Peasants, probably from 1590-1620, is the first truly masterly painting of this myth told in Ovid’s Metamorphoses, and for once an easel painting on canvas rather than a fresco. Although not a religious theme, this drew on the other acceptable source of narratives at the time, classical myth.

If there’s one artist who clearly defined the start of a new era it was Caravaggio, who began his career in Milan, but transformed art when he was painting in Rome.

His portrait of Narcissus from 1594-96 demonstrates how the tools of realism could be used in thoroughly secular paintings, but still of classical myth.

Caravaggio wasn’t alone. Among those who adopted and developed his style, the Caravaggists, was Lavinia Fontana, who came from Bologna and worked at the height of her career in Rome. Her Judith with the Head of Holofernes from 1600 also contrasts completely with the tondo Madonna by Raphael at the start of this article.

There was, of course, much more to the Baroque than Caravaggism. In 1604-06, Annibale Carracci and Domenichino (also from Bologna) joined forces in the Palazzo Farnese in Rome to paint this fresco of Perseus and Phineas. As Perseus stands in the centre brandishing the Gorgon’s face towards his attackers, Andromeda and her parents shelter behind, shielding their eyes for safety. The Renaissance was in the past, and Florence was no longer the beacon that it had been.

Signs of change occurred earlier in the north, where the first tentative steps were made towards a broadening of genres.

It was probably Hans Memling (c 1340-1494) who painted one of the first still lifes, on the back of a panel bearing a portrait of a young man praying, in about 1485. It has been proposed that this was part of a diptych or triptych, and could have formed its back cover when folded.

His choice of jug and flowers confirms its religious nature: Christ’s monogram is prominent on the body of the jug, and each of the flowers has specific references. Lilies refer to the purity of the Virgin Mary, the irises to her roles as Queen of Heaven and in the Passion, and the small aquilegia flowers have associations with the Holy Spirit. The eastern pattern on the rug is so distinctive of the artist that these became referred to as Memling rugs.

Coming closer to what was soon to become the Dutch Republic, Pieter Bruegel the Elder founded a dynasty of Flemish artists who broke from the Renaissance mould and started depicting the everyday.

Two of his major paintings from 1565 were formative influences on what was to come in the Dutch Golden Age. The Harvesters is a complete account of the grain harvest in the Low Countries, and Winter Landscape with Skaters and Bird Trap below is a pure landscape.

There are no figures particularly close by, and those on the ice are not demonstrating the many different activities they could be undertaking. It also happens that this was one of the first paintings to show Netherlandish people on the ice in the winter, a theme that shortly became very popular, and whose influence extended throughout Europe, across centuries and styles.

By 1600 the techniques of depicting the real world were well understood, and all it required was an abundant trade in art materials including drying oils and pigments, an increasingly wealthy population, seemingly insatiable demand for paintings, and an army of painters. Those all came in the Dutch Republic.